Development of a Model System for Tick-Borne Flavivirus Persistence in HEK 293T Cells
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چکیده
منابع مشابه
Development of a Model System for Tick-Borne Flavivirus Persistence in HEK 293T Cells
UNLABELLED We devised a model system to study persistent infection by the tick-borne flavivirus Langat virus (LGTV) in 293T cells. Infection with a molecularly cloned LGTV strain produced an acute lytic crisis that left few surviving cells. The culture was repopulated by cells that were ~90% positive for LGTV E protein, thus initiating a persistent infection that was maintained for at least 35 ...
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ژورنال
عنوان ژورنال: mBio
سال: 2015
ISSN: 2161-2129,2150-7511
DOI: 10.1128/mbio.00614-15